| Transactions |
| Date | Team | Player | Type | OthTm | EffDate | When |
| 4/10/2025 | KRK | Hamilton,D | Signed | | | Before |
| 4/10/2025 | KRK | O'Neill | Released | | | Before |
| 4/10/2025 | KRK | Wilson,Ja | Placed on Injured List | | 4/10/2025 | Before |
| 4/10/2025 | MAR | Beavers | Demoted to reserve roster | | | Before |
| 4/10/2025 | MAR | Cortes,C | Promoted to active roster | | | Before |
| 4/10/2025 | MAX | Blubaugh | Demoted to reserve roster | | | Before |
| 4/10/2025 | MAX | Freeland,K | Promoted to active roster | | | Before |
| 4/10/2025 | MAX | Horwitz | Demoted to reserve roster | | | Before |
| 4/10/2025 | MAX | Nunez,N | Promoted to active roster | | | Before |
| 4/10/2025 | MAX | Smith,P | Demoted to reserve roster | | | Before |
| 4/10/2025 | MAX | Sulser | Promoted to active roster | | | Before |
| 4/10/2025 | PSY | Wiemer | Promoted to active roster | | | Before |
| 4/10/2025 | PSY | Yastrzemski | Placed on Injured List | | 4/6/2025 | Before |
| 4/10/2025 | SED | Alvarez,A | Demoted to reserve roster | | | Before |
| 4/10/2025 | SED | Alvarez,A | Promoted to active roster | | | Before |
| 4/10/2025 | SED | Alvarez,F | Placed on Injured List | | 4/8/2025 | Before |
| 4/10/2025 | SED | Bautista | Placed on Injured List | | 4/9/2025 | Before |
| 4/10/2025 | SED | Falter | Signed | | | Before |
| 4/10/2025 | SED | Strowd | Promoted to active roster | | | Before |
| 4/10/2025 | SED | Taylor,Ty | Released | | | Before |
| 4/10/2025 | SED | Torrens | Promoted to active roster | | | Before |
| 4/10/2025 | SED | Woo | Placed on Injured List | | 4/4/2025 | Before |
| 4/10/2025 | STR | Hall | Demoted to reserve roster | | | Before |
| 4/10/2025 | STR | Henderson,L | Demoted to reserve roster | | | Before |
| 4/10/2025 | STR | Kelly,Mi | Promoted to active roster | | | Before |
| 4/10/2025 | STR | Murphy,C | Promoted to active roster | | | Before |
| 4/17/2025 | 755 | Leiter,J | Placed on Injured List | | 4/13/2025 | Before |
| 4/17/2025 | 755 | Lord | Promoted to active roster | | | Before |
| 4/17/2025 | BAR | Duran,E | Signed | | | Before |
| 4/17/2025 | BAR | O'Neill | Signed | | | Before |
| 4/17/2025 | BAR | Taylor,Ty | Signed | | | Before |
| 4/17/2025 | BMB | Amaya,M | Promoted to active roster | | | Before |
| 4/17/2025 | BMB | Fortes | Placed on Injured List | | 4/15/2025 | Before |
| 4/17/2025 | CTR | Roupp | Placed on Injured List | | 4/17/2025 | Before |
| 4/17/2025 | CTR | Soroka | Promoted to active roster | | | Before |
| 4/17/2025 | HWK | Dobbins | Promoted to active roster | | | Before |
| 4/17/2025 | HWK | Melton,T | Demoted to reserve roster | | | Before |
| 4/17/2025 | MAR | Beavers | Promoted to active roster | | | Before |
| 4/17/2025 | MAR | Freeman,T | Demoted to reserve roster | | | Before |
| 4/17/2025 | MAR | Freeman,T | Promoted to active roster | | | Before |
| 4/17/2025 | MAR | Merrill | Placed on Injured List | | 4/14/2025 | Before |
| 4/17/2025 | MAX | Freeland,K | Demoted to reserve roster | | | Before |
| 4/17/2025 | MAX | Horwitz | Promoted to active roster | | | Before |
| 4/17/2025 | MAX | Nunez,N | Demoted to reserve roster | | | Before |
| 4/17/2025 | MAX | Smith,P | Promoted to active roster | | | Before |
| 4/17/2025 | PSY | Bradish | Demoted to reserve roster | | | Before |
| 4/17/2025 | PSY | Fitzgerald,R | Promoted to active roster | | | Before |
| 4/17/2025 | PSY | Mauricio | Demoted to reserve roster | | | Before |
| 4/17/2025 | PSY | Oviedo | Promoted to active roster | | | Before |
| 4/17/2025 | PSY | Sproat | Promoted to active roster | | | Before |
| 4/17/2025 | PSY | Wiemer | Demoted to reserve roster | | | Before |
| 4/17/2025 | PSY | Woodruff | Demoted to reserve roster | | | Before |
| 4/17/2025 | PSY | Yastrzemski | Activated from Injured List | | | Before |
| 4/17/2025 | SED | Alvarez,A | Promoted to active roster | | | Before |
| 4/17/2025 | SED | Ibanez | Demoted to reserve roster | | | Before |
| 4/17/2025 | STR | Donovan | Placed on Injured List | | 4/13/2025 | Before |
| 4/17/2025 | STR | Enright | Promoted to active roster | | | Before |
| 4/17/2025 | STR | Murphy,C | Demoted to reserve roster | | | Before |
| 4/17/2025 | STR | Solano | Promoted to active roster | | | Before |
| 4/17/2025 | TBC | Carter | Promoted to active roster | | | Before |
| 4/17/2025 | TBC | Frelick | Placed on Injured List | | 4/15/2025 | Before |
| 4/24/2025 | HWK | Cameron,N | Promoted to active roster | | | Before |
| 4/24/2025 | HWK | Dobbins | Demoted to reserve roster | | | Before |
| 4/24/2025 | HWK | McLean | Demoted to reserve roster | | | Before |
| 4/24/2025 | HWK | Melton,T | Promoted to active roster | | | Before |
| 4/24/2025 | MAR | Beavers | Demoted to reserve roster | | | Before |
| 4/24/2025 | MAR | Merrill | Activated from Injured List | | | Before |
| 4/24/2025 | MAX | Blubaugh | Promoted to active roster | | | Before |
| 4/24/2025 | MAX | Freeland,K | Promoted to active roster | | | Before |
| 4/24/2025 | MAX | Lodolo | Demoted to reserve roster | | | Before |
| 4/24/2025 | MAX | Lopez,O | Placed on Injured List | | 4/24/2025 | Before |
| 4/24/2025 | MAX | Nunez,N | Promoted to active roster | | | Before |
| 4/24/2025 | MAX | Sulser | Demoted to reserve roster | | | Before |
| 4/24/2025 | PSY | Boyle | Promoted to active roster | | | Before |
| 4/24/2025 | PSY | Lopez,Ja | Placed on Injured List | | 4/18/2025 | Before |
| 4/24/2025 | SED | Alvarez,A | Demoted to reserve roster | | | Before |
| 4/24/2025 | SED | Alvarez,F | Activated from Injured List | | | Before |
| 4/24/2025 | SED | Bautista | Activated from Injured List | | | Before |
| 4/24/2025 | SED | Carroll | Placed on Injured List | | 4/19/2025 | Before |
| 4/24/2025 | SED | Falter | Demoted to reserve roster | | | Before |
| 4/24/2025 | SED | Ibanez | Promoted to active roster | | | Before |
| 4/24/2025 | SED | Johnson,B | Demoted to reserve roster | | | Before |
| 4/24/2025 | SED | Johnson,B | Promoted to active roster | | | Before |
| 4/24/2025 | SED | Strowd | Demoted to reserve roster | | | Before |
| 4/24/2025 | SED | Torrens | Demoted to reserve roster | | | Before |
| 4/24/2025 | SED | Torrens | Promoted to active roster | | | Before |
| 4/24/2025 | SED | Woo | Activated from Injured List | | | Before |
| 4/24/2025 | STR | Enright | Demoted to reserve roster | | | Before |
| 4/24/2025 | STR | Kelly,Mi | Demoted to reserve roster | | | Before |
| 4/24/2025 | STR | Misiorowski | Promoted to active roster | | | Before |
| 4/24/2025 | STR | Murphy,C | Promoted to active roster | | | Before |
| 4/24/2025 | TBU | Hoskins | Promoted to active roster | | | Before |
| 4/24/2025 | TBU | Langford | Placed on Injured List | | 4/21/2025 | Before |
| 4/24/2025 | TBU | Marte,N | Placed on Injured List | | 4/21/2025 | Before |
| 4/24/2025 | TBU | Stephenson,T | Promoted to active roster | | | Before |
| 4/30/2025 | BOM | Conine | Acquired via trade | HWK | | After |
| 4/30/2025 | BOM | Keith | Traded away | HWK | | After |
| 4/30/2025 | BOM | Rogers,Ty | Traded away | HWK | | After |
| 4/30/2025 | BOM | Weissert | Acquired via trade | HWK | | After |
| 4/30/2025 | HWK | Conine | Traded away | BOM | | After |
| 4/30/2025 | HWK | Keith | Acquired via trade | BOM | | After |
| 4/30/2025 | HWK | Rogers,Ty | Acquired via trade | BOM | | After |
| 4/30/2025 | HWK | Weissert | Traded away | BOM | | After |
| 5/1/2025 | BOM | Conine | Promoted to active roster | | | Before |
| 5/1/2025 | HWK | Anderson,G | Demoted to reserve roster | | | Before |
| 5/1/2025 | HWK | Melton,T | Demoted to reserve roster | | | Before |
| 5/1/2025 | HWK | Mountcastle | Placed on Injured List | | 4/29/2025 | Before |
| 5/1/2025 | HWK | Perkins,J | Promoted to active roster | | | Before |
| 5/1/2025 | HWK | Rodriguez,M | Promoted to active roster | | | Before |
| 5/1/2025 | MAX | Blubaugh | Demoted to reserve roster | | | Before |
| 5/1/2025 | MAX | Jackson,A | Promoted to active roster | | | Before |
| 5/1/2025 | MAX | Kim,Hy | Demoted to reserve roster | | | Before |
| 5/1/2025 | MAX | Lodolo | Promoted to active roster | | | Before |
| 5/1/2025 | MAX | Lopez,O | Activated from Injured List | | | Before |
| 5/1/2025 | MAX | Sulser | Promoted to active roster | | | Before |
| 5/1/2025 | MAX | Teel | Demoted to reserve roster | | | Before |
| 5/1/2025 | MAX | Trammell | Demoted to reserve roster | | | Before |
| 5/1/2025 | STR | Canning | Promoted to active roster | | | Before |
| 5/1/2025 | STR | Enright | Promoted to active roster | | | Before |
| 5/1/2025 | STR | Kelly,Mi | Promoted to active roster | | | Before |
| 5/1/2025 | STR | Miller,E | Demoted to reserve roster | | | Before |
| 5/1/2025 | STR | Morales | Promoted to active roster | | | Before |
| 5/1/2025 | STR | Murphy,C | Demoted to reserve roster | | | Before |
| 5/1/2025 | STR | Sale | Demoted to reserve roster | | | Before |
| 5/1/2025 | STR | Soriano,J | Demoted to reserve roster | | | Before |
| 5/1/2025 | TBC | Carter | Demoted to reserve roster | | | Before |
| 5/1/2025 | TBC | Frelick | Activated from Injured List | | | Before |
| 5/1/2025 | TBC | Gray,S | Demoted to reserve roster | | | Before |
| 5/1/2025 | TBC | King,M | Promoted to active roster | | | Before |
| 5/1/2025 | WHA | Bieber | Promoted to active roster | | | Before |
| 5/1/2025 | WHA | Carlson | Signed | | | Before |
| 5/1/2025 | WHA | Houser | Demoted to reserve roster | | | Before |
| 5/1/2025 | WHA | Sheets | Placed on Injured List | | 4/30/2025 | Before |
| 5/1/2025 | WHA | Tawa | Promoted to active roster | | | Before |
| 5/8/2025 | BMB | Amaya,M | Demoted to reserve roster | | | Before |
| 5/8/2025 | BMB | Bregman | Placed on Injured List | | 5/8/2025 | Before |
| 5/8/2025 | BMB | Fortes | Activated from Injured List | | | Before |
| 5/8/2025 | BMB | Schuemann | Promoted to active roster | | | Before |
| 5/8/2025 | MAX | Blubaugh | Promoted to active roster | | | Before |
| 5/8/2025 | MAX | Kim,Hy | Promoted to active roster | | | Before |
| 5/8/2025 | MAX | Nunez,N | Demoted to reserve roster | | | Before |
| 5/8/2025 | MAX | Sulser | Demoted to reserve roster | | | Before |
| 5/8/2025 | PSY | Lopez,Ja | Activated from Injured List | | | Before |
| 5/8/2025 | PSY | Sproat | Demoted to reserve roster | | | Before |
| 5/8/2025 | SED | Carroll | Activated from Injured List | | | Before |
| 5/8/2025 | SED | Torrens | Demoted to reserve roster | | | Before |
| 5/8/2025 | STR | Canning | Placed on Injured List | | 5/4/2025 | Before |
| 5/8/2025 | STR | Enright | Demoted to reserve roster | | | Before |
| 5/8/2025 | STR | Hall | Promoted to active roster | | | Before |
| 5/8/2025 | STR | Morales | Demoted to reserve roster | | | Before |
| 5/8/2025 | STR | Sale | Promoted to active roster | | | Before |
| 5/8/2025 | STR | Soriano,J | Promoted to active roster | | | Before |
| 5/15/2025 | BMB | Bregman | Activated from Injured List | | | Before |
| 5/15/2025 | BMB | Schuemann | Demoted to reserve roster | | | Before |
| 5/15/2025 | HWK | Dobbins | Promoted to active roster | | | Before |
| 5/15/2025 | HWK | Perkins,J | Demoted to reserve roster | | | Before |
| 5/15/2025 | KRK | Hamilton,D | Demoted to reserve roster | | | Before |
| 5/15/2025 | KRK | Wilson,Ja | Activated from Injured List | | | Before |
| 5/15/2025 | MAR | Freeman,T | Promoted to active roster | | | Before |
| 5/15/2025 | MAR | Garver | Signed | | | Before |
| 5/15/2025 | MAR | Garver | Signed | | | Before |
| 5/15/2025 | MAR | Garver | Demoted to reserve roster | | | Before |
| 5/15/2025 | MAR | Gil | Promoted to active roster | | | Before |
| 5/15/2025 | MAR | Sheehan | Placed on Injured List | | 5/14/2025 | Before |
| 5/15/2025 | MAR | Tolbert | Released | | | Before |
| 5/15/2025 | MAR | Tolbert | Released | | | Before |
| 5/15/2025 | MAX | Blubaugh | Demoted to reserve roster | | | Before |
| 5/15/2025 | MAX | Jackson,A | Demoted to reserve roster | | | Before |
| 5/15/2025 | MAX | Nunez,N | Demoted to reserve roster | | | Before |
| 5/15/2025 | MAX | Nunez,N | Promoted to active roster | | | Before |
| 5/15/2025 | MAX | Teel | Promoted to active roster | | | Before |
| 5/15/2025 | MAX | Trammell | Promoted to active roster | | | Before |
| 5/15/2025 | STR | Enright | Promoted to active roster | | | Before |
| 5/15/2025 | STR | Hall | Demoted to reserve roster | | | Before |
| 5/15/2025 | STR | Johnston | Promoted to active roster | | | Before |
| 5/15/2025 | STR | Kelly,Mi | Demoted to reserve roster | | | Before |
| 5/15/2025 | STR | Marsh | Demoted to reserve roster | | | Before |
| 5/15/2025 | STR | Morales | Promoted to active roster | | | Before |
| 5/15/2025 | STR | Murphy,C | Promoted to active roster | | | Before |
| 5/15/2025 | STR | Sale | Demoted to reserve roster | | | Before |
| 5/15/2025 | TBC | Gray,S | Promoted to active roster | | | Before |
| 5/15/2025 | TBC | King,M | Demoted to reserve roster | | | Before |
| 5/15/2025 | WHA | Bieber | Demoted to reserve roster | | | Before |
| 5/15/2025 | WHA | Houser | Promoted to active roster | | | Before |
| 5/15/2025 | WHA | Sheets | Activated from Injured List | | | Before |
| 5/15/2025 | WHA | Vargas,M | Placed on Injured List | | 5/10/2025 | Before |
| 5/22/2025 | MAX | Lopez,O | Placed on Injured List | | 5/22/2025 | Before |
| 5/22/2025 | MAX | Nunez,N | Promoted to active roster | | | Before |
| 5/22/2025 | MAX | Sulser | Promoted to active roster | | | Before |
| 5/22/2025 | MAX | Teel | Demoted to reserve roster | | | Before |
| 5/22/2025 | MAX | Teel | Promoted to active roster | | | Before |
| 5/22/2025 | MAX | Trammell | Demoted to reserve roster | | | Before |
| 5/22/2025 | SED | Alvarez,A | Promoted to active roster | | | Before |
| 5/22/2025 | SED | Bautista | Placed on Injured List | | 5/18/2025 | Before |
| 5/22/2025 | SED | Raley,B | Demoted to reserve roster | | | Before |
| 5/22/2025 | SED | Strowd | Promoted to active roster | | | Before |
| 5/22/2025 | STR | Donovan | Activated from Injured List | | | Before |
| 5/22/2025 | STR | Enright | Demoted to reserve roster | | | Before |
| 5/22/2025 | STR | Kelly,Mi | Promoted to active roster | | | Before |
| 5/22/2025 | STR | Miller,E | Promoted to active roster | | | Before |
| 5/22/2025 | STR | Misiorowski | Demoted to reserve roster | | | Before |
| 5/22/2025 | STR | Murphy,C | Demoted to reserve roster | | | Before |
| 5/22/2025 | STR | Sale | Promoted to active roster | | | Before |
| 5/22/2025 | STR | Solano | Demoted to reserve roster | | | Before |
| 5/28/2025 | BAR | Bender | Acquired via trade | MAX | | After |
| 5/28/2025 | BAR | Loftin | Traded away | MAX | | After |
| 5/28/2025 | MAR | Cortes,C | Traded away | MAX | | After |
| 5/28/2025 | MAR | Jobe | Traded away | MAX | | After |
| 5/28/2025 | MAR | Little,B | Acquired via trade | MAX | | After |
| 5/28/2025 | MAR | Meyers | Acquired via trade | MAX | | After |
| 5/28/2025 | MAX | Bender | Traded away | BAR | | After |
| 5/28/2025 | MAX | Cortes,C | Acquired via trade | MAR | | After |
| 5/28/2025 | MAX | Jobe | Acquired via trade | MAR | | After |
| 5/28/2025 | MAX | Little,B | Traded away | MAR | | After |
| 5/28/2025 | MAX | Loftin | Acquired via trade | BAR | | After |
| 5/28/2025 | MAX | Meyers | Traded away | MAR | | After |
| 5/29/2025 | BAR | Alcantara,Sa | Demoted to reserve roster | | | Before |
| 5/29/2025 | BAR | Hill,T | Promoted to active roster | | | Before |
| 5/29/2025 | BAR | Quintana | Placed on Injured List | | 5/24/2025 | Before |
| 5/29/2025 | BAR | Vest | Promoted to active roster | | | Before |
| 5/29/2025 | HWK | Cameron,N | Demoted to reserve roster | | | Before |
| 5/29/2025 | HWK | Casparius | Promoted to active roster | | | Before |
| 5/29/2025 | MAR | Alvarado,E | Signed | | | Before |
| 5/29/2025 | MAR | Alvarado,E | Demoted to reserve roster | | | Before |
| 5/29/2025 | MAR | Beavers | Demoted to reserve roster | | | Before |
| 5/29/2025 | MAR | Beavers | Promoted to active roster | | | Before |
| 5/29/2025 | MAR | Fermin,Jose | Released | | | Before |
| 5/29/2025 | MAX | Cortes,C | Demoted to reserve roster | | | Before |
| 5/29/2025 | MAX | Hagenman | Signed | | | Before |
| 5/29/2025 | MAX | Hernandez,H | Promoted to active roster | | | Before |
| 5/29/2025 | MAX | Jackson,A | Promoted to active roster | | | Before |
| 5/29/2025 | MAX | Jobe | Released | | | Before |
| 5/29/2025 | MAX | Loftin | Promoted to active roster | | | Before |
| 5/29/2025 | MAX | Sulser | Demoted to reserve roster | | | Before |
| 5/29/2025 | MAX | Sulser | Promoted to active roster | | | Before |
| 5/29/2025 | MAX | Teel | Demoted to reserve roster | | | Before |
| 5/29/2025 | PSY | Oviedo | Demoted to reserve roster | | | Before |
| 5/29/2025 | PSY | Sproat | Promoted to active roster | | | Before |
| 5/29/2025 | SED | Alvarez,A | Demoted to reserve roster | | | Before |
| 5/29/2025 | SED | Cruz,S | Signed | | | Before |
| 5/29/2025 | SED | Falter | Released | | | Before |
| 5/29/2025 | STR | Johnston | Demoted to reserve roster | | | Before |
| 5/29/2025 | STR | Marsh | Promoted to active roster | | | Before |
| 5/29/2025 | STR | Morales | Demoted to reserve roster | | | Before |
| 5/29/2025 | STR | Murphy,C | Promoted to active roster | | | Before |
| 5/29/2025 | TBU | Bello | Demoted to reserve roster | | | Before |
| 5/29/2025 | TBU | Langford | Activated from Injured List | | | Before |
| 5/29/2025 | TBU | Marte,N | Activated from Injured List | | | Before |
| 5/29/2025 | TBU | Monasterio | Promoted to active roster | | | Before |
| 5/29/2025 | TBU | Seager | Placed on Injured List | | 5/26/2025 | Before |
| 5/29/2025 | TBU | Stephenson,T | Demoted to reserve roster | | | Before |
| 6/5/2025 | BMB | Anderson,Ty | Promoted to active roster | | | Before |
| 6/5/2025 | BMB | Lively | Promoted to active roster | | | Before |
| 6/5/2025 | BMB | Schmidt | Placed on Injured List | | 6/1/2025 | Before |
| 6/5/2025 | BMB | Schuemann | Promoted to active roster | | | Before |
| 6/5/2025 | BMB | Strickland | Demoted to reserve roster | | | Before |
| 6/5/2025 | BMB | Tauchman | Placed on Injured List | | 5/28/2025 | Before |
| 6/5/2025 | BOM | Gorman | Signed | | | Before |
| 6/5/2025 | BOM | Vargas,I | Released | | | Before |
| 6/5/2025 | CTR | Kremer | Placed on Injured List | | 5/26/2025 | Before |
| 6/5/2025 | CTR | Roupp | Activated from Injured List | | | Before |
| 6/5/2025 | HWK | Cameron,N | Promoted to active roster | | | Before |
| 6/5/2025 | HWK | Casparius | Demoted to reserve roster | | | Before |
| 6/5/2025 | JAC | Garcia,LA | Demoted to reserve roster | | | Before |
| 6/5/2025 | JAC | McCutchen | Promoted to active roster | | | Before |
| 6/5/2025 | JAC | Rogers,Tr | Placed on Injured List | | 5/28/2025 | Before |
| 6/5/2025 | JAC | Walker,T | Promoted to active roster | | | Before |
| 6/5/2025 | MAX | Blubaugh | Promoted to active roster | | | Before |
| 6/5/2025 | MAX | Burger | Demoted to reserve roster | | | Before |
| 6/5/2025 | MAX | Cortes,C | Promoted to active roster | | | Before |
| 6/5/2025 | MAX | Hagenman | Released | | | Before |
| 6/5/2025 | MAX | Hernandez,H | Demoted to reserve roster | | | Before |
| 6/5/2025 | MAX | Loftin | Demoted to reserve roster | | | Before |
| 6/5/2025 | MAX | Lopez,O | Activated from Injured List | | | Before |
| 6/5/2025 | MAX | Martinez,J | Signed | | | Before |
| 6/5/2025 | MAX | Martinez,J | Demoted to reserve roster | | | Before |
| 6/5/2025 | MAX | Nunez,N | Demoted to reserve roster | | | Before |
| 6/5/2025 | MAX | Trammell | Promoted to active roster | | | Before |
| 6/5/2025 | PSY | Edman | Demoted to reserve roster | | | Before |
| 6/5/2025 | PSY | Mauricio | Promoted to active roster | | | Before |
| 6/5/2025 | PSY | Oviedo | Promoted to active roster | | | Before |
| 6/5/2025 | PSY | Sproat | Demoted to reserve roster | | | Before |
| 6/5/2025 | PSY | Woodruff | Demoted to reserve roster | | | Before |
| 6/5/2025 | PSY | Woodruff | Promoted to active roster | | | Before |
| 6/5/2025 | SED | Cruz,S | Demoted to reserve roster | | | Before |
| 6/5/2025 | SED | Cruz,S | Promoted to active roster | | | Before |
| 6/5/2025 | SED | Jobe | Signed | | | Before |
| 6/5/2025 | SED | Schneemann | Demoted to reserve roster | | | Before |
| 6/5/2025 | SED | Torrens | Released | | | Before |
| 6/5/2025 | STR | Henderson,L | Promoted to active roster | | | Before |
| 6/5/2025 | STR | Miller,E | Demoted to reserve roster | | | Before |
| 6/5/2025 | STR | Morales | Promoted to active roster | | | Before |
| 6/5/2025 | STR | Sale | Demoted to reserve roster | | | Before |
| 6/11/2025 | BMB | Soderstrom | Acquired via trade | KRK | | After |
| 6/11/2025 | KRK | Soderstrom | Traded away | BMB | | After |
| 6/11/2025 | MAR | Gaddis | Acquired via trade | WHA | | After |
| 6/11/2025 | MAR | Gil | Traded away | WHA | | After |
| 6/11/2025 | MAR | Houser | Acquired via trade | WHA | | After |
| 6/11/2025 | MAR | Megill,Ty | Traded away | WHA | | After |
| 6/11/2025 | WHA | Gaddis | Traded away | MAR | | After |
| 6/11/2025 | WHA | Gil | Acquired via trade | MAR | | After |
| 6/11/2025 | WHA | Houser | Traded away | MAR | | After |
| 6/11/2025 | WHA | Megill,Ty | Acquired via trade | MAR | | After |
| 6/12/2025 | BMB | Bauers | Demoted to reserve roster | | | Before |
| 6/12/2025 | BMB | Mitchell | Signed | | | Before |
| 6/12/2025 | HWK | Dobbins | Demoted to reserve roster | | | Before |
| 6/12/2025 | HWK | Maldonado,M | Demoted to reserve roster | | | Before |
| 6/12/2025 | HWK | McLean | Promoted to active roster | | | Before |
| 6/12/2025 | HWK | Ruiz,K | Promoted to active roster | | | Before |
| 6/12/2025 | KRK | Flexen | Promoted to active roster | | | Before |
| 6/12/2025 | KRK | Giolito | Placed on Injured List | | 6/12/2025 | Before |
| 6/12/2025 | KRK | Ozuna | Promoted to active roster | | | Before |
| 6/12/2025 | MAR | Alvarado,E | Demoted to reserve roster | | | Before |
| 6/12/2025 | MAR | Alvarado,E | Promoted to active roster | | | Before |
| 6/12/2025 | MAR | Alvarado,E | Promoted to active roster | | | Before |
| 6/12/2025 | MAR | Alvarado,E | Promoted to active roster | | | Before |
| 6/12/2025 | MAR | Campbell,K | Signed | | | Before |
| 6/12/2025 | MAR | Campbell,K | Demoted to reserve roster | | | Before |
| 6/12/2025 | MAR | Gil | Demoted to reserve roster | | | Before |
| 6/12/2025 | MAR | Lauer | Placed on Injured List | | 6/6/2025 | Before |
| 6/12/2025 | MAR | Ragans | Demoted to reserve roster | | | Before |
| 6/12/2025 | MAR | Ragans | Demoted to reserve roster | | | Before |
| 6/12/2025 | MAR | Saggese | Released | | | Before |
| 6/12/2025 | MAR | Sheehan | Activated from Injured List | | | Before |
| 6/12/2025 | MAR | Sheehan | Activated from Injured List | | | Before |
| 6/12/2025 | MAX | Blubaugh | Demoted to reserve roster | | | Before |
| 6/12/2025 | MAX | Burger | Promoted to active roster | | | Before |
| 6/12/2025 | MAX | Cortes,C | Placed on Injured List | | 6/6/2025 | Before |
| 6/12/2025 | MAX | Ellard | Signed | | | Before |
| 6/12/2025 | MAX | Hernandez,H | Promoted to active roster | | | Before |
| 6/12/2025 | MAX | Jackson,A | Demoted to reserve roster | | | Before |
| 6/12/2025 | MAX | Martinez,J | Released | | | Before |
| 6/12/2025 | MAX | Teel | Promoted to active roster | | | Before |
| 6/12/2025 | MOJ | Jensen | Demoted to reserve roster | | | Before |
| 6/12/2025 | MOJ | Maile | Signed | | | Before |
| 6/12/2025 | MOJ | Pfaadt | Released | | | Before |
| 6/12/2025 | SED | Alvarez,A | Promoted to active roster | | | Before |
| 6/12/2025 | SED | Bautista | Activated from Injured List | | | Before |
| 6/12/2025 | SED | Bautista | Demoted to reserve roster | | | Before |
| 6/12/2025 | SED | Bautista | Promoted to active roster | | | Before |
| 6/12/2025 | SED | Campbell,K | Released | | | Before |
| 6/12/2025 | SED | Jobe | Demoted to reserve roster | | | Before |
| 6/12/2025 | SED | Jobe | Promoted to active roster | | | Before |
| 6/12/2025 | SED | Jobe | Demoted to reserve roster | | | Before |
| 6/12/2025 | SED | McCullers | Signed | | | Before |
| 6/12/2025 | SED | Schneemann | Promoted to active roster | | | Before |
| 6/12/2025 | SED | Strowd | Demoted to reserve roster | | | Before |
| 6/12/2025 | SED | Westburg | Placed on Injured List | | 6/6/2025 | Before |
| 6/12/2025 | STR | Henderson,L | Demoted to reserve roster | | | Before |
| 6/12/2025 | STR | Misiorowski | Promoted to active roster | | | Before |
| 6/12/2025 | STR | Morales | Demoted to reserve roster | | | Before |
| 6/12/2025 | STR | Sale | Promoted to active roster | | | Before |
| 6/12/2025 | TBU | Bello | Promoted to active roster | | | Before |
| 6/12/2025 | TBU | Heineman | Demoted to reserve roster | | | Before |
| 6/12/2025 | TBU | Ray | Demoted to reserve roster | | | Before |
| 6/12/2025 | TBU | Stephenson,T | Promoted to active roster | | | Before |
| 6/12/2025 | WHA | Bieber | Promoted to active roster | | | Before |
| 6/12/2025 | WHA | Gil | Demoted to reserve roster | | | Before |
| 6/12/2025 | WHA | Martin,Ch | Promoted to active roster | | | Before |
| 6/12/2025 | WHA | Megill,Ty | Demoted to reserve roster | | | Before |
| 6/18/2025 | CTR | Campbell,K | Acquired via trade | MAR | | After |
| 6/18/2025 | CTR | Diaz,Yan | Traded away | MAR | | After |
| 6/18/2025 | CTR | Marte,K | Traded away | TBU | | After |
| 6/18/2025 | CTR | May | Acquired via trade | TBU | | After |
| 6/18/2025 | CTR | Mayer | Acquired via trade | MAR | | After |
| 6/18/2025 | CTR | Miller,Br | Acquired via trade | MAR | | After |
| 6/18/2025 | CTR | Monasterio | Acquired via trade | TBU | | After |
| 6/18/2025 | CTR | Suarez,Ro | Traded away | MAR | | After |
| 6/18/2025 | CTR | Turner,T | Traded away | MAR | | After |
| 6/18/2025 | CTR | Vesia | Traded away | TBU | | After |
| 6/18/2025 | MAR | Campbell,K | Traded away | CTR | | After |
| 6/18/2025 | MAR | Diaz,Yan | Acquired via trade | CTR | | After |
| 6/18/2025 | MAR | Mayer | Traded away | CTR | | After |
| 6/18/2025 | MAR | Miller,Br | Traded away | CTR | | After |
| 6/18/2025 | MAR | Suarez,Ro | Acquired via trade | CTR | | After |
| 6/18/2025 | MAR | Turner,T | Acquired via trade | CTR | | After |
| 6/18/2025 | TBU | Marte,K | Acquired via trade | CTR | | After |
| 6/18/2025 | TBU | May | Traded away | CTR | | After |
| 6/18/2025 | TBU | Monasterio | Traded away | CTR | | After |
| 6/18/2025 | TBU | Vesia | Acquired via trade | CTR | | After |
| 6/19/2025 | BMB | Haggerty | Released | | | Before |
| 6/19/2025 | CTR | Clase,E | Promoted to active roster | | | Before |
| 6/19/2025 | CTR | Koss | Promoted to active roster | | | Before |
| 6/19/2025 | CTR | Lowe,N | Signed | | | Before |
| 6/19/2025 | CTR | Megill,Tr | Promoted to active roster | | | Before |
| 6/19/2025 | CTR | Sweeney | Signed | | | Before |
| 6/19/2025 | HWK | McLean | Demoted to reserve roster | | | Before |
| 6/19/2025 | HWK | Melton,T | Promoted to active roster | | | Before |
| 6/19/2025 | MAR | Alvarado,E | Demoted to reserve roster | | | Before |
| 6/19/2025 | MAR | Clemens | Demoted to reserve roster | | | Before |
| 6/19/2025 | MAR | Freeman,T | Demoted to reserve roster | | | Before |
| 6/19/2025 | MAR | Lauer | Activated from Injured List | | | Before |
| 6/19/2025 | MAR | O'Hoppe | Released | | | Before |
| 6/19/2025 | MAR | Rushing | Signed | | | Before |
| 6/19/2025 | MAR | Rushing | Demoted to reserve roster | | | Before |
| 6/19/2025 | MAR | Warren,W | Demoted to reserve roster | | | Before |
| 6/19/2025 | MAX | Cortes,C | Activated from Injured List | | | Before |
| 6/19/2025 | MAX | Freeland,K | Released | | | Before |
| 6/19/2025 | MAX | Freeland,K | Demoted to reserve roster | | | Before |
| 6/19/2025 | MAX | Hernandez,H | Demoted to reserve roster | | | Before |
| 6/19/2025 | MAX | Jackson,A | Demoted to reserve roster | | | Before |
| 6/19/2025 | MAX | Jackson,A | Promoted to active roster | | | Before |
| 6/19/2025 | MAX | Kim,Hy | Demoted to reserve roster | | | Before |
| 6/19/2025 | MAX | Lawlar | Released | | | Before |
| 6/19/2025 | MAX | Nunez,N | Promoted to active roster | | | Before |
| 6/19/2025 | MAX | Ortiz,L | Signed | | | Before |
| 6/19/2025 | MAX | Rodriguez,Ed | Signed | | | Before |
| 6/19/2025 | MAX | Suarez,J | Demoted to reserve roster | | | Before |
| 6/19/2025 | MAX | Suarez,J | Promoted to active roster | | | Before |
| 6/19/2025 | MAX | Teel | Demoted to reserve roster | | | Before |
| 6/19/2025 | MAX | Teel | Promoted to active roster | | | Before |
| 6/19/2025 | PSY | Fermin,JM | Released | | | Before |
| 6/19/2025 | PSY | Fermin,JM | Signed | | | Before |
| 6/19/2025 | PSY | Fermin,Jose | Signed | | | Before |
| 6/19/2025 | PSY | Fitzgerald,R | Released | | | Before |
| 6/19/2025 | PSY | Nance | Demoted to reserve roster | | | Before |
| 6/19/2025 | PSY | Oviedo | Demoted to reserve roster | | | Before |
| 6/19/2025 | PSY | Slaten | Promoted to active roster | | | Before |
| 6/19/2025 | PSY | Wiemer | Promoted to active roster | | | Before |
| 6/19/2025 | PSY | Woodruff | Promoted to active roster | | | Before |
| 6/19/2025 | PSY | Yastrzemski | Placed on Injured List | | 6/18/2025 | Before |
| 6/19/2025 | SED | Cruz,S | Demoted to reserve roster | | | Before |
| 6/19/2025 | SED | Westburg | Activated from Injured List | | | Before |
| 6/19/2025 | STR | Canning | Activated from Injured List | | | Before |
| 6/19/2025 | STR | Miller,E | Promoted to active roster | | | Before |
| 6/19/2025 | STR | Misiorowski | Demoted to reserve roster | | | Before |
| 6/19/2025 | STR | Sale | Demoted to reserve roster | | | Before |
| 6/19/2025 | TBC | Eflin | Released | | | Before |
| 6/19/2025 | TBC | Young,C | Signed | | | Before |
| 6/19/2025 | TBU | Abel | Signed | | | Before |
| 6/19/2025 | TBU | Bernardino | Demoted to reserve roster | | | Before |
| 6/19/2025 | TBU | Hancock | Signed | | | Before |
| 6/19/2025 | TBU | Javier | Released | | | Before |
| 6/19/2025 | TBU | Matthews,Z | Released | | | Before |
| 6/19/2025 | TBU | Monasterio | Placed on Injured List | | 6/13/2025 | Before |
| 6/19/2025 | TBU | Ray | Promoted to active roster | | | Before |
| 6/19/2025 | TBU | Semien | Demoted to reserve roster | | | Before |
| 6/19/2025 | WHA | Bieber | Demoted to reserve roster | | | Before |
| 6/19/2025 | WHA | Gil | Promoted to active roster | | | Before |
| 6/19/2025 | WHA | Tawa | Demoted to reserve roster | | | Before |
| 6/19/2025 | WHA | Vargas,M | Activated from Injured List | | | Before |
| 6/25/2025 | 755 | Beavers | Acquired via trade | MAR | | After |
| 6/25/2025 | 755 | Clemens | Acquired via trade | MAR | | After |
| 6/25/2025 | 755 | Duran,Ja | Traded away | MAR | | After |
| 6/25/2025 | 755 | Laureano | Traded away | MAR | | After |
| 6/25/2025 | 755 | Rushing | Acquired via trade | MAR | | After |
| 6/25/2025 | 755 | Smith,J | Traded away | MAR | | After |
| 6/25/2025 | MAR | Beavers | Traded away | 755 | | After |
| 6/25/2025 | MAR | Clemens | Traded away | 755 | | After |
| 6/25/2025 | MAR | Duran,Ja | Acquired via trade | 755 | | After |
| 6/25/2025 | MAR | Laureano | Acquired via trade | 755 | | After |
| 6/25/2025 | MAR | Rushing | Traded away | 755 | | After |
| 6/25/2025 | MAR | Smith,J | Acquired via trade | 755 | | After |
| 6/26/2025 | BAR | Kim,Ha | Released | | | Before |
| 6/26/2025 | BAR | Lawlar | Signed | | | Before |
| 6/26/2025 | BMB | Anderson,Ty | Demoted to reserve roster | | | Before |
| 6/26/2025 | BMB | Schmidt | Activated from Injured List | | | Before |
| 6/26/2025 | HWK | Anderson,G | Promoted to active roster | | | Before |
| 6/26/2025 | HWK | Melton,T | Demoted to reserve roster | | | Before |
| 6/26/2025 | JAC | Rogers,Tr | Activated from Injured List | | | Before |
| 6/26/2025 | JAC | Walker,T | Demoted to reserve roster | | | Before |
| 6/26/2025 | MAR | Lauer | Demoted to reserve roster | | | Before |
| 6/26/2025 | MAR | Meyers | Demoted to reserve roster | | | Before |
| 6/26/2025 | MAR | Meyers | Promoted to active roster | | | Before |
| 6/26/2025 | MAR | Ragans | Demoted to reserve roster | | | Before |
| 6/26/2025 | MAR | Ragans | Promoted to active roster | | | Before |
| 6/26/2025 | MAR | Smith,J | Demoted to reserve roster | | | Before |
| 6/26/2025 | MAR | Torkelson | Demoted to reserve roster | | | Before |
| 6/26/2025 | MAX | Ashcraft,G | Signed | | | Before |
| 6/26/2025 | MAX | Blubaugh | Promoted to active roster | | | Before |
| 6/26/2025 | MAX | Burger | Demoted to reserve roster | | | Before |
| 6/26/2025 | MAX | Jackson,A | Promoted to active roster | | | Before |
| 6/26/2025 | MAX | Kim,Hy | Promoted to active roster | | | Before |
| 6/26/2025 | MAX | Nunez,N | Demoted to reserve roster | | | Before |
| 6/26/2025 | MAX | Sulser | Released | | | Before |
| 6/26/2025 | MAX | Teel | Demoted to reserve roster | | | Before |
| 6/26/2025 | PSY | Allen,N | Released | | | Before |
| 6/26/2025 | PSY | Deluca | Promoted to active roster | | | Before |
| 6/26/2025 | PSY | Javier | Signed | | | Before |
| 6/26/2025 | PSY | Wiemer | Demoted to reserve roster | | | Before |
| 6/26/2025 | PSY | Wiemer | Promoted to active roster | | | Before |
| 6/26/2025 | PSY | Wiemer | Demoted to reserve roster | | | Before |
| 6/26/2025 | PSY | Woodruff | Placed on Injured List | | 6/22/2025 | Before |
| 6/26/2025 | STR | Miller,E | Demoted to reserve roster | | | Before |
| 6/26/2025 | STR | Sale | Promoted to active roster | | | Before |
| 6/26/2025 | TBC | Fedde | Signed | | | Before |
| 6/26/2025 | TBC | Meadows | Released | | | Before |
| 6/26/2025 | WHA | Gil | Demoted to reserve roster | | | Before |
| 6/26/2025 | WHA | Megill,Ty | Promoted to active roster | | | Before |